King Æthelred I of Northumbria is murdered in Corbridge by a group led by his ealdormen, Ealdred and Wada. The patrician Osbald is crowned, but abdicates within 27 days.

Peace of Ferrara between Republic of Venice, Duchy of Milan, Republic of Florence and House of Gonzaga: ending of the second campaign of the Wars in Lombardy fought until the Treaty of Lodi in 1454, which will then guarantee the conditions for the development of the Italian Renaissance.

The cornerstone of the current St. Peter's Basilica is laid.

Bona Sforza is crowned as queen consort of Poland.

Trial of Martin Luther begins its second day during the assembly of the Diet of Worms. He refuses to recant his teachings despite the risk of excommunication.

Bostonians rise up in rebellion against Sir Edmund Andros.

Real Academia de la Historia ("Royal Academy of History") is founded in Madrid.

American Revolution: The British Army advances up the Charles River in Massachusetts to destroy supplies of American militias, while Paul Revere and other riders rapidly warn the countryside.

Three-Fifths Compromise: The first instance of black slaves in the United States of America being counted as three-fifths of persons (for the purpose of taxation), in a resolution of the Congress of the Confederation. This was later adopted in the 1787 Constitution.

War of the First Coalition: The Peace of Leoben is signed by Napoleon Bonaparte and Maximilian, Count of Merveldt, creating an armistice between France and Austria, setting the stage for the Treaty of Campo Formio and ending the War of the First Coalition.[citation needed]

The University of Alabama is founded in Tuscaloosa, Alabama.

American victory at the battle of Cerro Gordo opens the way for invasion of Mexico.